Holographic data storage in a DX-center material

We report on the optical storage of digital data in a semiconductor sample containing DX centers. The diffraction efficiency and the bit-error-rate performance of multiplexed data images are shown to agree well with a simple model of the material. Uniform storage without an exposure schedule is demonstrated. The volume sensitivity is found to be ~10^3 times that of LiNBO3:Fe. The importance of coherent addition of scattered light with diffracted light in holographic data storage is discussed

Program Synthesis using Natural Language

Interacting with computers is a ubiquitous activity for millions of people. Repetitive or specialized tasks often require creation of small, often one-off, programs. End-users struggle with learning and using the myriad of domain-specific languages (DSLs) to effectively accomplish these tasks. We present a general framework for constructing program synthesizers that take natural language (NL) inputs and produce expressions in a target DSL. The framework takes as input a DSL definition and training data consisting of NL/DSL pairs. From these it constructs a synthesizer by learning optimal weights and classifiers (using NLP features) that rank the outputs of a keyword-programming based translation. We applied our framework to three domains: repetitive text editing, an intelligent tutoring system, and flight information queries. On 1200+ English descriptions, the respective synthesizers rank the desired program as the top-1 and top-3 for 80% and 90% descriptions respectively

Attentional biases and PTSD symptomology in victims of sexual assault and motor vehicle accidents

While the field of change detection and attentional biases has become an increasingly popular area of study and much is already known about Posttraumatic Stress Disorder (PTSD), very little research has been done integrating these two areas. In the present study, we chose to investigate two types of traumatic experiences prevalent in the college population, motor vehicle accidents (MVAs) and sexual assaults. The flicker paradigm, used to measure change detection, was utilized to examine hypersensitivity to environments with threatening stimuli in individuals whom experienced either of these traumas. The paradigm monitored reaction times to identifying changes that took place in scenes involving MVA, suggested sexual aggression, or neutral stimuli. We hypothesized that those with higher levels of PTSD symptomology would respond faster to changes that represented their central clinical concern. The data suggested that there was a significant main effect for interaction between reaction times (RTs) to MVA stimuli and PTSD symptomology. However, the data did not indicate a significant main effect for interaction between PTSD symptomology and RTs for sexual aggression stimuli

AN INITIAL EVALUATION OF THE EFFECTIVENESS OF INTREO ACTIVATION REFORMS. ESRI RESEARCH SERIES NUMBER 81 MARCH 2019

This report presents results from an initial evaluation that the Economic and Social Research Institute (ESRI) has undertaken of the effectiveness of the most recent set of activation reforms that have been made to Ireland’s public employment services (PES). The modifications, which are known as the Intreo activation process reforms, were first introduced in 2012 for all newly unemployed Jobseeker’s Allowance (JA) and Jobseeker’s Benefit (JB) recipients only. The reforms have focused on making changes to how benefit and employment services are delivered to jobseekers as opposed to what types of employment services are delivered (i.e., job search assistance, training, education courses, etc.)

SEXUAL VS. ASEXUAL REPRODUCTION IN A STICK INSECT (MEGAPHASMA DENTRICUS)

The paradox of sex is one of biology’s great evolutionary questions, particularly in those species that are fully capable of sexual and asexual reproduction. To quantify how fitness varies between these two modes of reproduction, we explored lifetime fecundity in Megaphasma dentricus, the giant walking stick of North America. For the first 20 days of egg laying, there were no fecundity differences between mated and unmated females with respect to egg number or egg weight; all females laid a total of ~50 eggs and each egg weighed about 0.02g. For days 21-50 (the last 30 days of egg laying), unmated females laid significantly fewer (but not lighter) eggs than sexually reproducing females. Overall, lifetime fecundity in unmated females was about 5-10% less than mated females. Myriad factors remain unexplored in this species, including the ploidy of sexually and asexually produced eggs, the effects of parasites or other considerations of co-evolution (e.g., the Red Queen Hypothesis), and the accumulation of deleterious mutations (e.g., Muller’s Ratchet)

An Assessment of Data Related to Inspections of Risk Factors for Public Swimming Pools

Background: The Georgia Department of Public Health (DPH) is mandated to ensure that public swimming pools are safe for those who use them. This mandate is carried out by the DPH and local environmental health professionals through regulations and inspections. In 2015, legislation was introduced proposing to reduce the authority of the DPH to inspect certain pool types (apartments, subdivision, condominiums) and thus reduce regulatory protections in place for swimmers. To ensure that the DPH had current information on the risks associated with pools, the EH team, with assistance from a graduate student, analyzed inspection data to evaluate risk factors associated with these pool types and summarized drownings and waterborne disease outbreaks (WBDOs). Methods: Pool inspection data (n=4,441 pools) for 2014 were retrieved from the Environmental Health Information System (EHIS) of the DPH. Data from the 2010 Census and epidemiological data on drownings and water-borne disease outbreaks (WBDOs) were also evaluated. Data were stratified by public health district and type/number of pools and analyzed for selected violations of health risk factors (pH, barriers, disinfectant residual). Drownings and WBDOs were described and summarized. Results: Approximately 55% of inspected pools were for apartments, condominiums, and subdivisions. These pool types were consistently cited by inspectors for the selected risk factors and ranked in the top five for these violations. In 2013, children aged 1-17 had the highest percentage (30%) of deaths from drowning. In 2001-2014, there were 28 WBDOs, with 39% occurring at public pool venues. Conclusions: Data from this research provided information on risks associated with pools and supported the importance of inspection programs for public swimming pools. The data were used to inform policy makers on the risks associated with the pool venues under legislative review. These data, combined with other risk factor information, were utilized by the DPH to inform training needs and to reinforce public health messaging on protecting swimmer health

In silico karyotyping of chromosomally polymorphic malaria mosquitoes in the Anopheles gambiae complex

Chromosomal inversion polymorphisms play an important role in adaptation to environmental heterogeneities. For mosquito species in the Anopheles gambiae complex that are significant vectors of human malaria, paracentric inversion polymorphisms are abundant and are associated with ecologically and epidemiologically important phenotypes. Improved understanding of these traits relies on determining mosquito karyotype, which currently depends upon laborious cytogenetic methods whose application is limited both by the requirement for specialized expertise and for properly preserved adult females at specific gonotrophic stages. To overcome this limitation, we developed sets of tag single nucleotide polymorphisms (SNPs) inside inversions whose biallelic genotype is strongly correlated with inversion genotype. We leveraged 1,347 fully sequenced An. gambiae and Anopheles coluzzii genomes in the Ag1000G database of natural variation. Beginning with principal components analysis (PCA) of population samples, applied to windows of the genome containing individual chromosomal rearrangements, we classified samples into three inversion genotypes, distinguishing homozygous inverted and homozygous uninverted groups by inclusion of the small subset of specimens in Ag1000G that are associated with cytogenetic metadata. We then assessed the correlation between candidate tag SNP genotypes and PCA-based inversion genotypes in our training sets, selecting those candidates with >80% agreement. Our initial tests both in held-back validation samples from Ag1000G and in data independent of Ag1000G suggest that when used for in silico inversion genotyping of sequenced mosquitoes, these tags perform better than traditional cytogenetics, even for specimens where only a small subset of the tag SNPs can be successfully ascertained

Analytic perturbation theory in QCD and Schwinger's connection between the beta-function and the spectral density

We argue that a technique called analytic perturbation theory leads to a well-defined method for analytically continuing the running coupling constant from the spacelike to the timelike region, which allows us to give a self-consistent definition of the running coupling constant for timelike momentum. The corresponding $\beta$-function is proportional to the spectral density, which confirms a hypothesis due to Schwinger.Comment: 11 pages, 2 figure